Scutellarin ameliorates pulmonary fibrosis through inhibiting NF-κB/NLRP3-mediated epithelial–mesenchymal transition and inflammation
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چکیده
منابع مشابه
Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition
BACKGROUND Pulmonary fibrosis is a late manifestation of acute respiratory distress syndrome (ARDS). Sepsis is a major cause of ARDS, and its pathogenesis includes endotoxin-induced vascular injury. Recently, endothelial-to-mesenchymal transition (EndMT) was shown to play an important role in pulmonary fibrosis. On the other hand, dipeptidyl peptidase (DPP)-4 was reported to improve vascular dy...
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Objective: Activation of several signal transduction pathways, including cardiac inflammation and fibrosis, are important parts of structural and functional changes in diabetic cardiomyopathy (DCM), which is a leading cause of cardiovascular complications. NF-κB signaling pathway plays critical roles in promoting cardiac inflammation and cardiac fibrosis. It has been reported that hesperetin co...
متن کاملCorrigendum to “Suppressing Syndecan-1 Shedding Ameliorates Intestinal Epithelial Inflammation through Inhibiting NF-κB Pathway and TNF-α”
[This corrects the article DOI: 10.1155/2016/6421351.].
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ژورنال
عنوان ژورنال: Cell Death & Disease
سال: 2020
ISSN: 2041-4889
DOI: 10.1038/s41419-020-03178-2